PARAFORMALDEHYDE, 1KG

(HO(CH2O)nH; [30525-89-4]; FW~600
Fixative. Polyoxymethylene. White free-flowing solid pellet (prill) with strong, pungent formaldehyde odor. Avoid strong oxidizing agents, temperatures above 38°C.

Karnovsky MJ: A formaldehyde-glutaraldehyde fixative of high osmolarity for use in electron microscopy. J Cell Biol, 27, 137A, 1965

Note: Karnovsky's 1965 fixative contains 5% glutaraldehyde and 4% formaldehyde in a sodium cacodylate buffer and is very hypotonic (p. 5:1.17, alternative solution strength and formulation suggested)5. (Reference 5, p. 64)

Robertson JD: The occurrence of a subunit pattern in the unit membranes of club endings in Maunther cell synapses in gold fish brain. J Cell Bio, 19, 201, 1963